"SUBOXONE, NALOXONE, OXYCODONE, OXYMORPHONE, NALBUPHINE AND OTHER SUCH "THEBAINE" DERIVED"
PLEASE CONSIDER THAT SUBOXONE MAY VERY WELL BE THE MOST DANGEROUS DRUG THAT HAS EVER BEEN APPROVED BY OUR GOVERNMENT. IF YOU WANT, TRUE AND ACCURATE INFORMATION ON SUBOXONE PLEASE READ THE FOLLOWING. AN INFORMATIVE DOCUMENT WHICH EXPLORES THE TRUE NATURE AND DANGERS OF SUBOXONE, SUBUTEX, AND NARCAN (NALOXONE). THERE IS ALSO SOME INFORMATION INTO THE NATURE OF PURE AGONIST DRUGS SUCH AS MORPHINE OR OXYCODONE. PLEASE READ FOR YOUR OWN SAFETY. IT IS COMPLEX BUT I HAVE TRIED TO EDIT IT AS TO MAKE IT ACCESSIBLE TO EVERYONE. IF YOU WANT TO BE RID OF YOUR ADDICTION THEN GET OFF THE DRUGS. SWAPPING ONE ADDITION FOR ANOTHER IS JUST PLAIN STUPID AND THE FACILITIES OUT THERE THAT ARE DOING THIS ARE OUT FOR ONE THING AND ONE THING ONLY, YOUR MONEY. DO NOT FALL INTO THEIR TRAP
Each section of discussion of this drug will also have the reference used, gathered at the end. I have also comment at the bottom of some sections.
"HISTORY"
The first thing to understand is a little history of the medication. Buprenorphine, which is four, parts of the medication Suboxone. It is a semi-synthetic opiate with partial agonist and antagonist action. Buprenorphine hydrochloride was first marketed in the 1980s by Reckitt & Colman as an analgesic available generally as Temgesic 0.2 mg sublingual tablets and as Buprenex in a 0.3 mg/ml injectable formulation. In October 2002, the Food and Drug Administration additionally approved Suboxone and Subutex, Buprenorphine's high-dose sublingual pill preparations for opioid addiction, and as such, the drug is now used for this purpose. In the European Union, Suboxone and Subutex, were approved for opioid addiction treatment in September 2006.
In the Netherlands, Buprenorphine is a List II drug of the Opium Law, though special rules and guidelines apply to its prescription and dispensation. In the USA, it has been a Schedule III drug under the United Nations Convention on Psychotropic Substances since it was rescheduled from Schedule V just before FDA approval of Suboxone and Subutex. In the recent years, Buprenorphine has been introduced in most European countries as a transdermal formulation for the treatment of chronic pain.
What is misleading about this information is it never mention the other ligand that is in Suboxone, "Naloxone", however if you read on in this document it does mention that Suboxone contains the opioid antagonist Naloxone to deter the abuse of the tablets by intravenous injection. A good analogy to this would be like putting rat poison in cigarettes to deter people from smoking. It is pure insanity and very bad medicine even by Western standards but most addiction practitioners using Suboxone just do not see it this way. The fact is Narcan was developed to spare an overdose victim from death but when used in this manner the person is left with half a liver. What do you suppose chronic use of Suboxone(Narcan) is going to do to a persons liver"
"A BIT OF REALITY"
Following is information about a death due to an overdose from Suboxone.
"The recent Suboxone-related deaths of two Milwaukee-area residents have drawn negative attention to federal rules that allow patients to use the buprenorphine-based drug at home, the Milwaukee-Wisconsin journal Sentinel reported April 2, 2009. Some local officials blame wider availability of the drug for increasing the risk of abuse by recreational users. Milwaukee police said they saw evidence of illicit trafficking of Suboxone even before it was linked to the overdose deaths of these two teenage students. Chuck Wood of the Waukesha County Sheriff's Department said informants noted that a street market for the drug has developed because recreational users have found a way to use Suboxone to get high. Suboxone was specifically designed to limit abuse potential by including the opiate antagonist Naloxone in the formulation. It was going to be so controlled, Wood said. Now we are seeing it out in the community. An official with the federal Substance Abuse & Mental Health Services Administration (SAMHSA) said the overdose deaths seem to be the tragic results of abuse rather than any inherent danger in Suboxone. Suboxone is a very safe drug, said Robert Lubran, SAMHSA's director of pharmacologic therapies. There is a reason why they are controlled substances -- because they are abusable. It really does its job well, said Jim Aker, a counselor at ProHealth Care, a program in Waukesha that has used Suboxone to treat 140 recovering addicts during the past two years. Police believe that the two overdose deaths were the result of ingesting Suboxone along with other substances; some users incorrectly believe that Suboxone mitigates the effects of other drugs. Tim Baxter, medical director of Reckitt Benckiser Pharmaceuticals Inc., said Suboxone alone could not trigger a fatal overdose. Nevertheless, he said it has been linked to 15 deaths nationally when combined with alcohol or other drugs. Baxter said abuse has been tapering off, as drug users discover Suboxone's limited potential for intoxication. Some kids will decide, oh, this sounds like fun, we will have a go, Baxter said. They may try it once, but they go on to something else."
There is an enormous amount of fabrication and misinformation within this article and the standard of keeping the public misinformed continues. First off, Suboxone does only one thing for the addicted person, move them from one addition to another. I would like to ask Robert Lubran how many of the addicts that they think are recovered are actually completely off narcotics since Suboxone is a narcotic. The other thing is the inaccuracy about its mitigation qualities. It will mitigate other narcotic preparation since Naloxone is a pure antagonist and Buprenorphine partially agonizes and antagonizes its effect on narcotic receptors. Also, remember that since both Buprenorphine and Naloxone come from the same part of the poppy, "thebaine", you can expect withdrawal symptoms from both drugs when you try to stop taking Suboxone. Another issue is that Buprenorphine is the only synthetic narcotic that attaches itself to something other than the traditional receptor. It also binds with great affinity to the allosteric receptor with very little explanation as to why it does this. I believe binding to this receptor is what makes Suboxone so difficult to withdrawal from or have withdrawal last for 20 - 30 days. Read further on and you will understand.
The above article was taken from this internet site,
"ADDICTION"
The word addiction is difficult to understand since it is used in so many different contexts. Addiction has been used in referring to drug addiction, video game addiction, crime, money, work addiction, compulsive overeating, problem gambling, computer addiction, nicotine addiction, pornography addiction, etc.
In medicine, addiction refers to a chronic neurobiological illness that is characterized by having a genetic, psychosocial, and environmental component. Drug addiction, having a multi-component nature, is also characterized by the continued use of a, typically narcotic or euphoria inducing substance, despite its negative effects, impaired control over its use (compulsive behavior), and preoccupation with obtaining more (i.e. craving the drug). Street addiction is often accompanied by the existence of abnormal behaviors that parallels the escalating use of street drugs such as sex for money, B&E (breaking and Entering) and higher order crime. The further escalation of drug use will result in expanding criminal enterprise for the sale and distribution. Much money can be made by creating a large mass of addicted drones.
However, much larger sums have been made by our medical system for the number of medically addicted drones that have also been created. Deviant behavior can be characteristic of either street or medical drug addiction since the effects are the same, however, with most medical addicts where pain is the issue the continued use of narcotics will generally exacerbate their symptoms rather than control them.
The unfortunate fact is that all chronic use of a narcotic or other addictive substances will always result in addiction. Narcotics and drugs like them have a nature that once you become accustom to their effect stopping becomes impossible. There is factual medical evidence that suggests doctors have been covering up this fact for hundreds of years. If you are a sufferer of chronic pain, such as arthritis and fibermialgia then narcotics in general are a very poor choice. There is evidence to suggest that short-term use of narcotics can be beneficial to the surgery patient or to over come a traumatic injury, however the systematic regimented use over a long term will always be problematic, always.
Tolerance to a drug and physical dependence are defining characteristics of drug addiction however, other forms of addiction do exists. These other forms of addiction, such as video game addiction or gambling are not defined by physical changes but are strictly characterized by a mental condition, weakness in character, or usually mental trauma. One can think of the addiction as a residual by-product of the original trauma that simple needs to be dealt with. Typically when the addicted person deals with the trauma or conflict the addiction dissolves. It should always be carefully considered when attempted to assist addicted individuals. Much harm can be done if a professional expertise in the particular affliction has not been obtained.
Tolerance is often defined as a pharmacologic phenomenon where a medication needs to be continually increased to maintain the same effect. Individuals with chronic pain taking opiates like morphine, oxycotin or hydrocodone that need to continually increase the dose in order to maintain the drug's pain-relieving effects are said to have develop a tolerance. Tolerance is often used in medical circles to lessen the impact to the patient while allowing the addition go unchecked.
Addiction to a drug or Tolerance to a drug, effectively the same, will always result in physical dependency. Physical dependence means that if a certain drug is sharply discontinued, an individual will experience withdrawal symptoms with a severity commensurate to the amount of drug and longevity of use. Some of the drugs used for therapeutic purposes within our medical system that produce physical dependency and therefore withdrawal symptoms when abruptly stopped are oral steroids, certain antidepressants, benzodiazepines, and opiates.
"THE WAISMANN METHOD"
Buprenorphine offers some advantages over methadone, a common replacement therapy for opiate addiction it is longer-lasting so patients may not have to take it as often as methadone and buprenorphine offers patients the convenience of an at home supply, whereas those on methadone must report daily to a clinic to receive their dose. Opiate replacement or maintenance therapy may be helpful for many in the withdrawal phase of treatment to help patients ease off opiates. The problem is its potential for abuse and dependence, which may require a second detox. Swapping one addiction for another is not the answer. There are safe, medically supervised treatments for opiate addiction, including those drugs used in replacement therapy. Opiate-free treatment programs are ideal for those who wish to become completely independent from narcotic medications.
Buprenorphine detox performed with the Waismann Method a medical procedure under anesthesia that induce and speed the withdrawal while the patient sleeps. Buprenorphine addiction is a serious problem in the United States and tends to happen quickly and to unsuspecting individuals who have been prescribed Buprenorphine for legitimate pain reasons. The addiction creeps up quickly and once you have a Buprenorphine addiction, chances are it is too late to find an easy solution to get off Buprenorphine. The Buprenorphine detox treatment is performed in a full service hospital under the strict supervision of one of our medical directors. You are followed every step of the way from admission to release are assisted in creating a plan for remaining opiate-free once you complete your Buprenorphine detox.
It must be said that not everyone is a proponent of this method of detox but it is far better then most other methods that include more opiate use. Those facilities that use any method that includes additional narcotic use are extending the addiction. There is only one true method that will release you from narcotic addiction. Stop taking narcotics, period. It must be done safely and supervised especially for the hopelessly addicted. It must always be stressed that the hope of being free of the addiction must always be the, "Prize for the Effort", "The Light at the End of the Tunnel" and "The Hope for a Better Day". However, the inherent risked involved with the abuse or use of Suboxone is seldom discussed in any articles or reference books that can be researched. Only when the clinician takes an unbiased look at the drug do you ever hear some of the inherent risks. It is never discussed by any individual physicians involved in treating addicts with Suboxone. According to these individuals, Suboxone is a wonder drug. Please read on as the most serious dangers of this drug are approached.
The above information was taken from the internet site,
"PHARMACOLOGY AND PHARMACOKINETICS"
Buprenorphine is a "thebaine" derivative with powerful analgesia approximately twenty-five to forty times as potent as morphine. Thebaine (paramorphine) is an opiate alkaloid. A minor constituent of opium, thebaine is chemically similar to both morphine and codeine, but has stimulatory rather than depressant effects, causing strychnine-like convulsions at higher doses. Strychnine is a very toxic, colorless crystalline alkaloid used as a pesticide, particularly for killing small vertebrates such as birds and rodents. Strychnine causes muscular convulsions and eventually death through asphyxia or sheer exhaustion. Strychnine is only being used as a comparison to the ultimate effect of paramorphine at higher doses.
Thebaine is not used therapeutically, but can be converted industrially into a variety of compounds including oxycodone, oxymorphone, nalbuphine, naloxone, naltrexone buprenorphine and etrophine. Buprenorphine"s analgesic effect is due to partial agonist activity at µ-opioid receptors, i.e., when the molecule binds to a receptor, it is less likely to transduce a response in contrast to a full agonist such as morphine. An agonist versus an antagonist is a drug that alters the activity of a receptor, narcotic receptors in this case, throughout the nervous system.
Buprenorphine also has very high binding affinity for the receptor such that opioid receptor antagonist like naloxone only partially reverse its effects. Biochemical receptors are large protein molecules that can be activated by the binding of hormones or drugs also chemically referred to as a ligand. Receptors can be membrane-bound, occurring on the cell membrane of cells, or intracellular, such as on the nucleus or mitochondrion.
Binding occurs as a result of noncovalent interaction between the receptor and its ligand, at locations called the binding site on the receptor. A receptor may contain one or more binding sites for different ligands. Binding to the active site on the receptor regulates receptor activation directly.
The activity of receptors can also be regulated by the binding of a ligand to other sites on the receptor, as in allosteric binding sites. Antagonists mediate their effects through receptor interactions by preventing agonist-induced responses. This may be accomplished by binding to the active site or the allosteric site. In addition, antagonists may interact at unique binding sites not normally involved in the biological regulation of the receptor's activity to exert their effects.
These two properties must be carefully considered by the practitioner, as an overdose cannot be easily reversed. An important note is overdose is unlikely in addicted patients or people with tolerance to opioids who use the drug sublingually as meant in the case of Subutex/Suboxone, especially if there are no benzodiazepines involved. Persons with a seizure disorder, whom are also addicted to narcotics, present a particular difficulty since a benzodiazepine may be necessary for seizure control. Onset of withdrawal can and often causes those already susceptible to seizures a threshold break. Persons with seizure disorders should never be put on Suboxone regardless of their past opiate use. Another approach should be used.
Suboxone use in persons physically dependant on full-agonist opioids, without first waiting for expiration of the agonist's half-life, may trigger full opioid withdrawal that also cannot be easily reversed and can last over twenty-four hours, as Suboxone's mean half-life is thirty-seven hours. This will mean that if the antagonist finds it way to the receptor without the benefit of Buprenorphine also binding to the receptor an addict may go into deadly precipitated withdrawal. Buprenorphine is also a k-opioid receptor antagonist, and partial/full agonist at the recombinant human ORL1 nociceptin receptor also known as the NOP receptor.
Buprenorphine hydrochloride, administered by intramuscular injection, intravenous infusion, via a transdermal patch, or as a sublingual tablet is not usually ingestible, due to very high first-pass liver metabolism. However, there is an ethanolic solution used orally for minimal analgesic effects and the sublingual tablet gain access to the blood stream via vein infiltration under the tongue. Buprenorphine is metabolized by the liver via the CYP3A4 isozyme of the cytochrome P450 enzyme system into norbuprenorphine by N-dealkylation, glucuronidation and other metabolites. The metabolites are further conjugated with glucuronic acid and eliminated mainly through excretion into the bile. The elimination half-life of buprenorphine is 20"73 hours (mean 37). Due to the mainly hepatic elimination, there is no risk of accumulation in patients with renal impairment and in the elderly. However, individuals with hepatic disease or hepatic issues should never be put on Buprenorphine or Naloxone products due to hepatic impact.
The main active metabolite, norbuprenorphine, is a d-opioid receptor and ORL1 receptor agonist and µ- and ?-opioid receptor partial agonist. However, buprenorphine antagonizes its effects at the ?-opioid receptor. Plasma concentrations after application of transdermal buprenorphine increase steadily and the minimum effective therapeutic dose (100 pg/ml) is reached at eleven hours and twenty-one hours for a single 35 and 70 transdermal patch, respectively. Peak plasma concentration (Cmax) is reached in about sixty hours (305 and 624 pg/ml for the 35 and 70 strength transdermal patch, respectively), and is markedly longer than with 0.3 mg intravenous buprenorphine (0.41 hours). Transdermal buprenorphine has a half-life of approximately thirty hours, and a bioavailability of approximately 50%, which is comparable to sublingual buprenorphine.
Although the previous section was very technical a minimal understanding of synthetic narcotics should have been obtained. Narcotics by their very nature are dangerous and can be very deadly but our own medical system has turned the natural already dangerous qualities of opium into a forty to fifty times more perilous. To truly retreat from western medicine one must commit to never using substances like narcotics. However, with that said should a doctor whisper in you ear, "Take the pain relief or you may die from the pain", then you may want to reconsider your position. After the crisis is over however, you can return to your stance against synthetic substances. Another issue is not to be fooled by the term, "Partial Synthetic". Either a substance is natural or synthetic, it cannot be both.
"ABUSE"
Buprenorphine is also used recreationally, typically by opioid users and the potential for abuse is much greater than previously considered. Typical effects include analgesia, a sense of euphoria and increased verbal communication. Due to the high potency of tablet forms of buprenorphine, only a small amount of the drug need be ingested to achieve the desired effects. If you consider the nature of buprenorphine, with its difficulty with ingestion due to the first pass function of the liver, you can then understand why the tablets are so potent. Then considering the other factors concerning the binding affinity and strength, twenty-five to forty times greater than morphine, intravenous drug users become particularly susceptible to overdose. An overdose, which will be nearly impossible to reverse since narcan (Naloxone) only partially, reversing its effect.
The buprenorphine preparation, Suboxone, comes in an orange lemon-lime flavored tablet for sublingual administration. The taste of Suboxone is described by some to be very unpleasant. Possible explanations for unpleasant taste could be the bitter taste of the buprenorphine itself. The unpleasant taste could also be acting as a deterrent to abuse and was done intentionally by the pharmaceutical company, Reckitt Benckiser.
Buprenorphine abuse is very common in Scandinavia, especially in Finland and Sweden where in 2007, the authorities in Uppsala county in Sweden confiscated more buprenorphine than cocaine, ecstasy and GHB combined. In Finland, from 2005 to 2006, illegal use of Subutex (commonly intravenously) has preceded the large number of amphetamine usage. Intravenous administration of dissolved Subutex pills and insufflations of pulverized pills are the most common ways of recreational buprenorphine use.
"A HIDDEN DANGER AND ANOTHER DETOX"
Since there is very little written about what is being suggested here, support for any conclusion is difficult at best to find. When you consider Methadone(Dolophine) and the resulting death from that addiction substitute, Suboxone has a much greater potential to cause death. Since the pharmacology of buprenorphine states that the first-pass action of the liver will remove such a large percentage of the ligand Buprenorphine, then another approach was needed to get the opioid into the system. So sublingually was considered and developed but due to the overwhelming presser to have this drug controlled both from a drug classification as well as from having Naloxone (generic name Narcan) joined alongside the Buprenorphine to prevent abuse.
This is what then the problem becomes, should someone swallow this pill instead of keeping it under his or her tongue to dissolve you may be slammed into the worst precipitated withdrawal symptoms imaginable. Typically, the potential for seizures, heart stoppage, breathing difficulties and many other issues may be realized from swallowing Suboxone preparations.
Methadone maintenance was without this problem yet an unmanaged number of deaths were attributed to it. Buprenorphine's, with its difficulty ingesting, while still using it as an ingestible version will always have great potential for abuse since such a large amount of Buprenorphine has to be used. Both Suboxone as well as Methadone suffers from this susceptibility.
Since it is also true that the patient must be fully half life depleted of their current narcotic and in the throws of withdrawal before the Suboxone can be administered it seems idiotic to put them right back on another narcotic. You will inevitably need another detox from the Suboxone and Suboxone addiction will be the hardest of all to kick. There is a lot of different information being passed on the internet about Suboxone. It is being said that Suboxone works by, "Closing the door halfway and will help ease the addicted individual off the drug addiction". It has also been stated that the Suboxone is used to help allow the addict to, "Straighten up their lives by having their addiction controlled and off street drugs". Do not listen to this psychobabble because Suboxone is for one thing and one thing only, "To perpetuate your addiction and keep you coming back to spend more money on detox". Find a facility that is all about getting free of the addiction. Their out there you just have to be willing to look real hard, ask a lot of questions and learn a lot about your addiction. Another narcotic will always extend you addiction and never ever assit you in anyway. You want off narcotics then get of them, it is very hard, but it can be done and without the use of poisons like Suboxone!
"A FINAL OPINION"
Note that the article taken from the Milwaukee- Wisconsin journal Sentinel never mentions whether or not these 140 recovering addicts have ever gotten off Suboxone. Everyone seems to think that this drug is the golden gateway to opiate addiction and getting off narcotics, this simply is NOT true. What needs to be statistically gathered is how many addicts are now off the Suboxone after being treated with it. Since almost all addicts are sent on there way still on Suboxone the success of Suboxone is never really statistically gather since true success mean getting off narcotics entirely. The statistics being gathered referring to a, "Successful Course of Treatment", refers only to getting an addict onto Suboxone. There are no statistics as of yet as to how many actually are getting completely off narcotics. This statistic, the true statistic, will be much lower than what treatment facilities are currently expressing. Another very serious issue with Suboxone is that due to its inherently long half-life some folk are stopping cold turkey but suddenly find out on the third day that this was a big mistake. Now they are without any Suboxone and in the worst withdrawal of their lives. Many of these unfortunate individuals are killing themselves feeling they have no other alternative. PLEASE AVOID THIS BY UNDERSTANDING WHAT YOU ARE TAKING AND HOW IT WORKS. NO ONE CAN STOP TAKING SUBOXONE WITHOUT SEVER WITHDRAWAL ISSUES. Indicative of this issue Suboxone clinics are closing all over the US. Many doctors are finding out that they cannot get their addiction patients off the drug so they are simple abandoning the practice to move on to dollar greener pastures while simple abandoning these individual. This is also resulting in numerous suicides. Since these unfortunate individuals kill themselves the fact that is was related to Suboxone is never being established. When the true death toll from this drug finally comes out it will be in the millions.
In addition, notice that in the Milwaukee-Wisconsin journal Sentinel article they never mention that the other drugs they are referring to are not other narcotic preparations since the antagonist, Naloxone does its job by repelling all other forms of narcotics. However, it will only be a short time before a young street chemist finds a way to remove the Naloxone to leave only the Buprenorphine, unless this has already been achieved. Oh what each table of Suboxone will reap for this chemist, referring to the previously mentioned fact about Buprenorphine needing to be eighty percent of the tablets content. After this occurs, then Suboxone may become the most abuse narcotic substance known and it will quickly rival methadone for the number of deaths.
Although Methadone(Dolophine) is much like Buprenorphine without the Naloxone, it is far better controlled but even that control has left hundreds of thousands dead. Suboxone is a drug that should have never been approved by the FDA. It is much worst than the Methadone since Naloxone is so harsh to the liver as well as the Buprenorphine. Naloxone was never ever meant to be used on a regular basis. It was designed to save a person from a lethal overdose, but even then, it leaves that person with half a liver. It is a big money market for treatment facilities and pharmacies throughout the world.
Before long, the entire world is going to be addicted to Buprenorphine in one form or another it is just a matter of time. New compounds are being tested for use everyday. Right now they are looking into an anti-depressant uses for this drug. Suboxone will not get an addict off narcotics it only switched them from one narcotic addiction to another. However, due to the still powerful effects of euphoria, as well as other addictive quantities within Suboxone, since it is entirely of thebaine, it will be more difficult to overcome then what most addicts were on. Another approach for addiction treatment should be considered and if you have a Liver difficulty in any form this drug should not be used. If there is a history of seizures, this drug should not be used. The fact is there are so many contraindications for this drug it basically should never be used for anything.
Remember the commercial that refers to your brain on drug and then they fry an egg to further demonstrate the concern. Well just replace "drugs" with "Suboxone" and this is an accurate picture for anyone that goes on this drug. There is one striking difference in the second pitcher, the egg explodes. There will be a very good chance they will never get off it alive. Since this document attempts to provide complete and thorough information about Suboxone, Subutex and other narcotics there is only one real conclusion, "SUBOXONE IS A POISON AND CAN BE DEADLY TO EVERYONE THAT TAKES IT".
One last issue to revisit again about Suboxone are the deaths that are occurring but are never statistically gathered as related to Suboxone. Many people are finding themselves able to abandon Suboxone use cold turkey but when the third day arrives they are slammed into the worst withdrawal in their lives. Many are choosing to end their pain by ending their lives and these lives are documented as suicides not drug related. Unfortunately many will die before anything is done!
"SUBOXONE ENUMERATED CONCERNS"
1. Not nearly enough information is being provided before individuals are being put on Buprenorphine products and most information is inaccurate.
2. The death toll from this drug may yet rival any other drug in use today, many as a result of suicide.
3. If you truly want off drugs then get off them, do not just switch your habits to yet another drug.
4. If you have seizures or Liver issues DO NOT GO ON THIS PRODUCT. It could mean quick death for your Liver or an impossibility to get off. Since you cannot use benzodiazepines individuals with seizure concerns could be quickly put in a life-threatening situation. Benzodiazepines are drugs often used to treat Epilepsy. There is yet very little statistical information on these facts.
5. If you have started using Suboxone then try to get help from the others that are on this drug. Go to the chat rooms and see what others are saying about this drug. There may be something there that can help. Bottom line, do not try to detox on your own since it very well could kill you. However if you have been placed in a situation that you have no other choice but to detox on your own, please refer to addendum one; "Titration Schedule for Suboxone". You can do this, I did and I was addicted to narcotic for twenty-two years. Please do not consider this an endorsement of Suboxone, I despise the use, abuse, and misinformation about the drug. I am that individual that was placed in a life threaten situation. I have both liver disease and epilepsy and if I did not get very enthusiastic with my reduction of Suboxone I was going to die. I did it and so can you! Once again this is not an endorsement for the use of Suboxone.If you are not on this drug, DO NOT CONSIDER ITS USE.
6. Inappropriate use of Suboxone and misunderstanding about the drug will continue to cause deaths that go unexplained. The accidental ingestion of the Suboxone tablets will always have inherent risks for the addict trying to get off drugs. If they are ingested directly then withdrawal will follow however, due to the lack of accurate statistical gathering and misinformation, Suboxone use will always be problematic at best.
7. Abuse is still only at the infancy of this drug and when more is leant by those that would abuse then abuse will become rampant. The nature of Suboxone will always make it a very attractive drug providing you can remove the Narcan. Even with the Narcan the euphoria from Suboxone is far greater than published which will always make this drug attractive.
DO NOT GO ON SUBOXONE OR SUBUTEX. YOU MAY NEVER GET OFF THEM ALIVE.
Please remember this was only my educated opinion if you are considering treatment with this drug for an addiction please get educated first.
This document was constructed from a great deal of research done by the author but inevitable it is still the opinion of the author. It is based on over 200 hours of research as well as the authors own experience with Suboxone.
Dr. Julian R. Gothican
CREDENTIALS: PhD; Computer Science Other Degrees; and Physics, Mathematics and Pharmacology
"REFERENCE"
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"ADDENDUM ONE"
"TITRATION SCHEDULE"
Started Suboxone on May 22nd being moved from Kadian 200mg TPD, to it. Was put on 8mg Sublingual Tab ThPD 8:00am, 4:00pm and when I retired around 11pm. On June 1st I insisted on leaving but just three days prior I withdrew from all the medication. Two full days later is when I began to feel any withdraw symptoms and this is due to Buprenorphine half life potential, the mean is 37 hours I made it a full 48 hours. I return to a regiment of two 8mg sublingual pill one at 9:30am and one at 9:30pm after taking it Three PD for 8 days. I took 8mg TPD from June 1 to June 30th. On July 1, I reduced once again to 2mg TPD. On July 2nd @ approximately 11:50pm, I began to feel withdrawal symptoms so I used the 8mg pill I was carrying for this purpose. So let us see I went 7 + 24 + 24 + 23 = 78 hours. If my real start date is the 30th then my hours are not as impressive but still good at 55 hours respectively. I will try for at least 72 hours again and see what will happen. I will continue on the 2 mg until I need another 8mg.
Well on June 29th at 5pm, I moved from the 8mg to the 2mg TPD now at 5pm and 5am after having taken the 8mg TPD for 30 days. I will also carry a larger 8mg pill with me so as to ward off any intruding withdrawal but only if necessary. Yesterday July 3rd I concluded that I might have withdrawn a bit too fast to I went to 2mg three times a day. This still reduces my dos by 10mg per day, which is very enthusiastic, but I think I can do it. I may yet be able to withdraw from the medication this way all together and long before my supply runs out. On July 1st and July 12th I had to take, an extra pill to ward off withdraw but this was the only time. On July 27th, I moved from 2mg TPD to 1mg TPD. I will also carry an extra pill with me for when I need it but my hopes is to move to just one mg per day or .5mg TPD. On July 28th I needed to take my 1mg pill piece early but I still plan to keep it twice per day but since I took the final pill for the 27th early I will simply move the hours from 6am-6pm to 3am-3pm. 3am is when I took my second 1 mg pill which was only three hours early and it stopped all withdraw. Again, on Aug 3 and 5th, I had to take an extra 1mg and 2mg respectively to ward off withdraw again but I remained on 1mg TPD. Since I have been on 1mg TPD for ten days now but continue to need an occasional enhancement, I will extend my stay on 1mg TPD an additional week. Therefore, after three weeks on that, I will begin to use .5 TPD and then two-three weeks later abandon use but will continue to carry a pill for when I need it. I will need 26 mg of Suboxone to finish out the titration and be off the poison. On August 11th, I finally moved to .5 twice a day and continued to August 16th when I began to release myself from this addiction. I will continue to take .5 but only when I need the drug to ward off withdrawal. Expect to be completely off the drug by mid September. I was a bit late with my September prediction but I did meet my goal of Narcotic free in 2010. On Sunday December 27th two days after Christmas I took my very last dose of Suboxone. Today is January 2nd and I am doing OK! The first five days were hell incarnate but I am still alive and doing well on January 2nd narcotic free. HOOORAAAAYYYY! This is my eighteenth day off Suboxon and it has been a very long haul but I am finally getting over it however my sleep schedule has yet to return, sleep still comes very difficult. Final entry it is now twenty days off and I am finally begun to sleep better. Remember everything they tell you about this drug is a lie the withdrawal will last longer than any drug you have ever taken!
"SCHEDULE"
"24mg for 8days. (8mg *ThrPD) 16mg for 30days. (8mg **TPD) 6mg for 14days. (2mg ThrPD) 4mg for 14days. (2mg TPD) 2mg for 30days. (1mg TPD) 1mg for 60days. (.5mg TPD) .5mg for 60days. (1/4mg TPD) Abandon use on December27th, 2009.
* Three Per Day **Two Per Day
Important Note
Please do not misunderstand my willingness to provide this schedule. It is NOT an endorsement of Suboxone use. I do not recommend anyone using this product, since it is a poison but if you find yourself on it due to misinformation than a Titration schedule will still be needed. I cannot guarantee this schedule will work for you but this is the schedule I used. I was forced to detox on my own. After each facility I contacted learned of my other problems, I was dropped like a lead balloon by each one of them. I contacted a total of 729 Facilities across this country and was refused by everyone.
"MY ADDICTION PRAY"
"I pray that Jesus Christ, the Angles, Saints and everyone within feeling distance will look over me as I wonder into unfamiliar territory". "I pray that I can look to my weaknesses for strength and use my strength to find my weaknesses". "I ask this in the name of Jesus Christ to His Father and mine; He/She/It that is without a Name, the one we call our God". "I also pray to everyone"s own interpretation of God, Islam, Budism, Judaism, Hinduism, Jainism and Confucius, and all the religious leaders and prophets from all religions on Earth". "I ask all that is holly in the, 'Above', and the, 'Below', to gather strength in my name and pass it to me when I become the weakest". "I again ask this in the name of my God, The Father, The Son and the Holly Ghost, and all that ever walked the Earth and suffered from the iniquities of self righteous human beings or the poisons of man"s own creation." "I pray that I might be able to overlook the harm that I have done to myself and the harm others have done to me and forgive as I would hope to be forgiven". "I pray this in my name and the name of everyone that has ever had their sole trapped in an addiction and may that we all be safely released from our addiction and pain." An Addicts Prayer.
I forgive my Father for everything he did to me intentionally or unintentionally for his sole was trapped in an addiction to narcotics provided once again by our wonderful medical system in this country, the VA. I also forgive my Brother for killing himself for he to was addicted to narcotics!
Written by Dr. Julian Gothican
To capitulated compassion, unconditional love, and devotion to my Wife, Children and the, "Whole Human Race", I give you this knowledge free and without obligation to me or anyone else.
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